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Phosphorylation and Dephosphorylation of Tau Protein During Synthetic Torpor

Tau protein is of primary importance for many physiological processes in neurons, where it affects the dynamics of the microtubule system. When hyperphosphorylated (PP-Tau), Tau monomers detach from microtubules and tend to aggregate firstly in oligomers, and then in neurofibrillary tangles, as it o...

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Detalles Bibliográficos
Autores principales: Luppi, Marco, Hitrec, Timna, Di Cristoforo, Alessia, Squarcio, Fabio, Stanzani, Agnese, Occhinegro, Alessandra, Chiavetta, Pierfrancesco, Tupone, Domenico, Zamboni, Giovanni, Amici, Roberto, Cerri, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563845/
https://www.ncbi.nlm.nih.gov/pubmed/31244617
http://dx.doi.org/10.3389/fnana.2019.00057