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Essential long-range action of Wingless/Wnt in adult intestinal compartmentalization

Signal transduction activated by Wingless/Wnt ligands directs cell proliferation and fate specification in metazoans, and its overactivation underlies the development of the vast majority of colorectal cancers. In the conventional model, the secretion and movement of Wingless to cells distant from i...

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Detalles Bibliográficos
Autores principales: Tian, Ai, Duwadi, Deepesh, Benchabane, Hassina, Ahmed, Yashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563961/
https://www.ncbi.nlm.nih.gov/pubmed/31194729
http://dx.doi.org/10.1371/journal.pgen.1008111