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Activating Killer-cell Immunoglobulin-like Receptor genes confer risk for Crohn’s disease in children and adults of the Western European descent: Findings based on case-control studies

BACKGROUND: Killer-cell Immunoglobulin-like Receptor (KIR) genes encode receptors, which are mainly expressed on, and control functional activities of, Natural Killer (NK) cells. There exist six distinct activating KIR genes in humans, who differ from one another with respect to the repertoire of th...

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Detalles Bibliográficos
Autores principales: Samarani, Suzanne, Mack, David R., Bernstein, Charles N., Iannello, Alexandre, Debbeche, Olfa, Jantchou, Prevost, Faure, Christophe, Deslandres, Colette, Amre, Devendra K., Ahmad, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563976/
https://www.ncbi.nlm.nih.gov/pubmed/31194766
http://dx.doi.org/10.1371/journal.pone.0217767