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Behavioral and neurological analyses of adult mice carrying null and distinct loss-of-receptor function mutations in protein tyrosine phosphatase receptor type Z (PTPRZ)

Protein tyrosine phosphatase receptor type Z (PTPRZ) is preferentially expressed in the central nervous system as two transmembrane receptor isoforms PTPRZ-A/B and one secretory isoform PTPRZ-S. Ptprz-knockout mice lacking the expression of all three isoforms show behavioral, learning, and neurologi...

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Detalles Bibliográficos
Autores principales: Tanga, Naomi, Kuboyama, Kazuya, Kishimoto, Ayako, Kihara, Miho, Kiyonari, Hiroshi, Watanabe, Toshio, Fujikawa, Akihiro, Noda, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563982/
https://www.ncbi.nlm.nih.gov/pubmed/31194769
http://dx.doi.org/10.1371/journal.pone.0217880