A standardised framework to identify optimal animal models for efficacy assessment in drug development

INTRODUCTION: Poor translation of efficacy data derived from animal models can lead to clinical trials unlikely to benefit patients–or even put them at risk–and is a potential contributor to costly and unnecessary attrition in drug development. OBJECTIVES: To develop a tool to assess, validate and c...

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Detalles Bibliográficos
Autores principales: S. Ferreira, Guilherme, Veening-Griffioen, Désirée H., Boon, Wouter P. C., Moors, Ellen H. M., Gispen-de Wied, Christine C., Schellekens, Huub, van Meer, Peter J. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563989/
https://www.ncbi.nlm.nih.gov/pubmed/31194784
http://dx.doi.org/10.1371/journal.pone.0218014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563989/
https://www.ncbi.nlm.nih.gov/pubmed/31194784
http://dx.doi.org/10.1371/journal.pone.0218014

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