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Evolution of interface binding strengths in simplified model of protein quaternary structure

The self-assembly of proteins into protein quaternary structures is of fundamental importance to many biological processes, and protein misassembly is responsible for a wide range of proteopathic diseases. In recent years, abstract lattice models of protein self-assembly have been used to simulate t...

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Detalles Bibliográficos
Autores principales: Leonard, Alexander S., Ahnert, Sebastian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6564041/
https://www.ncbi.nlm.nih.gov/pubmed/31158218
http://dx.doi.org/10.1371/journal.pcbi.1006886