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Exploring E-cadherin-peptidomimetics interaction using NMR and computational studies

Cadherins are homophilic cell-cell adhesion molecules whose aberrant expression has often been shown to correlate with different stages of tumor progression. In this work, we investigate the interaction of two peptidomimetic ligands with the extracellular portion of human E-cadherin using a combinat...

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Detalles Bibliográficos
Autores principales: Civera, Monica, Vasile, Francesca, Potenza, Donatella, Colombo, Cinzia, Parente, Sara, Vettraino, Chiara, Prosdocimi, Tommaso, Parisini, Emilio, Belvisi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6564044/
https://www.ncbi.nlm.nih.gov/pubmed/31158220
http://dx.doi.org/10.1371/journal.pcbi.1007041