Methylomics analysis identifies a putative STAT3 target, SPG20, as a noninvasive epigenetic biomarker for early detection of gastric cancer

Gastric cancer is a leading cause of cancer worldwide. Our previous studies showed that aberrant activation of JAK/STAT3 signaling confer epigenetically silences STAT3 target genes in gastric cancer. To further investigate the clinical significance of this phenomenon, we performed Illumina 850K meth...

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Detalles Bibliográficos
Autores principales: Wei, Kuo-Liang, Chou, Jian-Liang, Chen, Yin-Chen, Jin, Hongchuan, Chuang, Yu-Min, Wu, Cheng-Shyong, Chan, Michael W. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6564691/
https://www.ncbi.nlm.nih.gov/pubmed/31194837
http://dx.doi.org/10.1371/journal.pone.0218338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6564691/
https://www.ncbi.nlm.nih.gov/pubmed/31194837
http://dx.doi.org/10.1371/journal.pone.0218338

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