Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction

Macrophages promote both injury and repair following myocardial infarction, but discriminating functions within mixed populations remains challenging. Here we used fate mapping and single-cell transcriptomics to demonstrate that at steady state, TIMD4(+)LYVE1(+)MHC-II(lo)CCR2(−) resident cardiac mac...

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Detalles Bibliográficos
Autores principales: Dick, Sarah A, Macklin, Jill A, Nejat, Sara, Clemente-Casares, Xavier, Momen, Abdul, Kantores, Crystal, Hosseinzadeh, Siyavash, Barbu, Iulia, Chen, Jinmiao, Althagafi, Marwan G, Besla, Rickvinder, Wong, Anthony, Aronoff, Laura, Zaman, Rysa, Lavine, Kory J, Razani, Babak, Ginhoux, Florent, Husain, Mansoor, Cybulsky, Myron I, Robbins, Clinton S, Epelman, Slava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565365/
https://www.ncbi.nlm.nih.gov/pubmed/30538339
http://dx.doi.org/10.1038/s41590-018-0272-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565365/
https://www.ncbi.nlm.nih.gov/pubmed/30538339
http://dx.doi.org/10.1038/s41590-018-0272-2

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