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Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model
The cholesterol-lowering drug lovastatin corrects neurological phenotypes in animal models of fragile X syndrome (FX), a commonly identified genetic cause of autism and intellectual disability (ID). The therapeutic efficacy of lovastatin is being tested in clinical trials for FX; however, the struct...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Society for Neuroscience
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565377/ https://www.ncbi.nlm.nih.gov/pubmed/31147392 http://dx.doi.org/10.1523/ENEURO.0097-19.2019 |