Estradiol induces BDNF/TrkB signaling in triple-negative breast cancer to promote brain metastases

Breast cancer brain metastases (BM) affect younger women disproportionally, including those lacking estrogen receptor (ER), progesterone receptor, and HER2 (known as triple-negative breast cancer; TNBC). Previous studies in preclinical models showed that pre-menopausal levels of estradiol (E2) promo...

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Detalles Bibliográficos
Autores principales: Contreras-Zárate, Maria J., Day, Nicole L., Ormond, D. Ryan, Borges, Virginia F., Tobet, Stuart, Gril, Brunilde, Steeg, Patricia S., Cittelly, Diana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565485/
https://www.ncbi.nlm.nih.gov/pubmed/30796353
http://dx.doi.org/10.1038/s41388-019-0756-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565485/
https://www.ncbi.nlm.nih.gov/pubmed/30796353
http://dx.doi.org/10.1038/s41388-019-0756-z

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