MicroRNA-1205, encoded on chromosome 8q24, targets EGLN3 to induce cell growth and contributes to risk of castration-resistant prostate cancer

The chromosome 8q24.21 locus, which contains the proto-oncogene c-MYC, long non-coding RNA PVT1, and microRNAs (miRs), is the most commonly amplified region in human prostate cancer. A long-range interaction of genetic variants with c-MYC or long non-coding PVT1 at this locus contributes to the gene...

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Detalles Bibliográficos
Autores principales: Wang, Yicun, Li, Xin, Liu, Wei, Li, Bingjin, Chen, Dongquan, Hu, Fengping, Wang, Lizhong, Liu, Xiaoguang M., Cui, Ranji, Liu, Runhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565506/
https://www.ncbi.nlm.nih.gov/pubmed/30808975
http://dx.doi.org/10.1038/s41388-019-0760-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565506/
https://www.ncbi.nlm.nih.gov/pubmed/30808975
http://dx.doi.org/10.1038/s41388-019-0760-3

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