Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc(1):aa(3) in Mycobacterium tuberculosis

The influence of carbon metabolism on oxidative phosphorylation is poorly understood in mycobacteria. M. tuberculosis expresses two respiratory terminal oxidases, the cytochrome bc(1):aa(3) and the cytochrome bd oxidase, which are jointly required for oxidative phosphorylation and mycobacterial viab...

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Detalles Bibliográficos
Autores principales: Kalia, Nitin P., Shi Lee, Bei, Ab Rahman, Nurlilah B., Moraski, Garrett C., Miller, Marvin J., Pethe, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565617/
https://www.ncbi.nlm.nih.gov/pubmed/31197236
http://dx.doi.org/10.1038/s41598-019-44887-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565617/
https://www.ncbi.nlm.nih.gov/pubmed/31197236
http://dx.doi.org/10.1038/s41598-019-44887-9

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