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Therapeutic effects of a novel BAFF blocker on arthritis

B-cell targeted therapy is effective for autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis (RA), although there are setbacks in RA clinical trials. In this study, we designed a novel B-cell activating factor (BAFF) antagonist: BAFF-Trap, a recombinant glycoprotein wit...

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Detalles Bibliográficos
Autores principales: Zhou, Bailing, Zhang, Hailong, Su, Xiaoqing, Luo, Yi, Li, Xiaopeng, Yu, Chaoheng, Xie, Qibing, Xia, Xuyang, He, Gu, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565627/
https://www.ncbi.nlm.nih.gov/pubmed/31231554
http://dx.doi.org/10.1038/s41392-019-0051-z