The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo

Prion-like domains (PLDs), defined by their low sequence complexity and intrinsic disorder, are present in hundreds of human proteins. Although gain-of-function mutations in the PLDs of neuronal RNA-binding proteins have been linked to neurodegenerative disease progression, the physiological role of...

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Detalles Bibliográficos
Autores principales: Vijayakumar, Jeshlee, Perrois, Charlène, Heim, Marjorie, Bousset, Luc, Alberti, Simon, Besse, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565635/
https://www.ncbi.nlm.nih.gov/pubmed/31197139
http://dx.doi.org/10.1038/s41467-019-10554-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565635/
https://www.ncbi.nlm.nih.gov/pubmed/31197139
http://dx.doi.org/10.1038/s41467-019-10554-w

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