Rif1 promotes association of G-quadruplex (G4) by its specific G4 binding and oligomerization activities

Rif1 is a conserved protein regulating replication timing and binds preferentially to the vicinity of late-firing/dormant origins in fission yeast. The Rif1 binding sites on the fission yeast genome have an intrinsic potential to generate G-quadruplex (G4) structures to which purified Rif1 preferent...

Descripción completa

Detalles Bibliográficos
Autores principales: Masai, Hisao, Fukatsu, Rino, Kakusho, Naoko, Kanoh, Yutaka, Moriyama, Kenji, Ma, Yue, Iida, Keisuke, Nagasawa, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565636/
https://www.ncbi.nlm.nih.gov/pubmed/31197198
http://dx.doi.org/10.1038/s41598-019-44736-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565636/
https://www.ncbi.nlm.nih.gov/pubmed/31197198
http://dx.doi.org/10.1038/s41598-019-44736-9

Ejemplares similares