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Rif1 promotes association of G-quadruplex (G4) by its specific G4 binding and oligomerization activities
Rif1 is a conserved protein regulating replication timing and binds preferentially to the vicinity of late-firing/dormant origins in fission yeast. The Rif1 binding sites on the fission yeast genome have an intrinsic potential to generate G-quadruplex (G4) structures to which purified Rif1 preferent...
Autores principales: | Masai, Hisao, Fukatsu, Rino, Kakusho, Naoko, Kanoh, Yutaka, Moriyama, Kenji, Ma, Yue, Iida, Keisuke, Nagasawa, Kazuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565636/ https://www.ncbi.nlm.nih.gov/pubmed/31197198 http://dx.doi.org/10.1038/s41598-019-44736-9 |
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