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Simulating multiple faceted variability in single cell RNA sequencing

The abundance of new computational methods for processing and interpreting transcriptomes at a single cell level raises the need for in silico platforms for evaluation and validation. Here, we present SymSim, a simulator that explicitly models the processes that give rise to data observed in single...

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Detalles Bibliográficos
Autores principales: Zhang, Xiuwei, Xu, Chenling, Yosef, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565723/
https://www.ncbi.nlm.nih.gov/pubmed/31197158
http://dx.doi.org/10.1038/s41467-019-10500-w