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Simulating multiple faceted variability in single cell RNA sequencing
The abundance of new computational methods for processing and interpreting transcriptomes at a single cell level raises the need for in silico platforms for evaluation and validation. Here, we present SymSim, a simulator that explicitly models the processes that give rise to data observed in single...
Autores principales: | Zhang, Xiuwei, Xu, Chenling, Yosef, Nir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565723/ https://www.ncbi.nlm.nih.gov/pubmed/31197158 http://dx.doi.org/10.1038/s41467-019-10500-w |
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