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Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy

Temperature is a key factor for determining the lifespan of both poikilotherms and homeotherms. It is believed that animals live longer at lower body temperatures. However, the precise mechanism remains largely unknown. Here, we report that autophagy serves as a boost mechanism for longevity at low...

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Detalles Bibliográficos
Autores principales: Chen, Yuan-Li, Tao, Jun, Zhao, Pei-Ji, Tang, Wei, Xu, Jian-Ping, Zhang, Ke-Qin, Zou, Cheng-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565724/
https://www.ncbi.nlm.nih.gov/pubmed/31197136
http://dx.doi.org/10.1038/s41467-019-10475-8