Determination of the degree of PEGylation of protein bioconjugates using data from proton nuclear magnetic resonance spectroscopy

The average number of methoxy poly(ethylene glycol) (mPEG) chains grafted to a protein – also known as the degree of PEGylation – is a fundamental parameter for characterizing a bioconjugate. The degree of PEGylation is typically determined by chromatographic or electrophoretic methods, which are su...

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Detalles Bibliográficos
Autores principales: Zaghmi, Ahlem, Greschner, Andrea A., Mendez-Villuendas, Eduardo, Liu, Jun Yang, de Haan, Hendrick W., Gauthier, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565728/
https://www.ncbi.nlm.nih.gov/pubmed/31223640
http://dx.doi.org/10.1016/j.dib.2019.104037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565728/
https://www.ncbi.nlm.nih.gov/pubmed/31223640
http://dx.doi.org/10.1016/j.dib.2019.104037

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