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Determination of the degree of PEGylation of protein bioconjugates using data from proton nuclear magnetic resonance spectroscopy
The average number of methoxy poly(ethylene glycol) (mPEG) chains grafted to a protein – also known as the degree of PEGylation – is a fundamental parameter for characterizing a bioconjugate. The degree of PEGylation is typically determined by chromatographic or electrophoretic methods, which are su...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565728/ https://www.ncbi.nlm.nih.gov/pubmed/31223640 http://dx.doi.org/10.1016/j.dib.2019.104037 |