Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development

The epidermal barrier is thought to protect sensory nerves from overexposure to environmental stimuli, and barrier impairment leads to pathological conditions associated with itch, such as atopic dermatitis (AD). However, it is not known how the epidermal barrier continuously protects nerves for the...

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Detalles Bibliográficos
Autores principales: Takahashi, Sonoko, Ishida, Azusa, Kubo, Akiharu, Kawasaki, Hiroshi, Ochiai, Sotaro, Nakayama, Manabu, Koseki, Haruhiko, Amagai, Masayuki, Okada, Takaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565750/
https://www.ncbi.nlm.nih.gov/pubmed/31197234
http://dx.doi.org/10.1038/s41598-019-44866-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565750/
https://www.ncbi.nlm.nih.gov/pubmed/31197234
http://dx.doi.org/10.1038/s41598-019-44866-0

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