A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia

Contractile to synthetic phenotypic switching of smooth muscle cells (SMCs) contributes to stenosis in vascular disease and vascular transplants. To generate more contractile SMCs, we performed a high-throughput differentiation screen using a MYH11-NLuc-tdTomato human embryonic stem cell reporter ce...

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Detalles Bibliográficos
Autores principales: Zhang, Jue, McIntosh, Brian E., Wang, Bowen, Brown, Matthew E., Probasco, Mitchell D., Webster, Sarah, Duffin, Bret, Zhou, Ying, Guo, Lian-Wang, Burlingham, William J., Kent, Craig, Ferris, Michael, Thomson, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565755/
https://www.ncbi.nlm.nih.gov/pubmed/31080110
http://dx.doi.org/10.1016/j.stemcr.2019.04.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565755/
https://www.ncbi.nlm.nih.gov/pubmed/31080110
http://dx.doi.org/10.1016/j.stemcr.2019.04.013

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