Cathepsin S acts via protease-activated receptor 2 to activate sensory neurons and induce itch-like behaviour

Chronic itch is a debilitating condition characterised by excessive scratching and is a symptom frequently reported in skin diseases such as atopic dermatitis. It has been proposed that release of the cysteine protease Cathepsin S (CatS) from skin keratinocytes or immune cells resident in or infiltr...

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Detalles Bibliográficos
Autores principales: Chung, Keshi, Pitcher, Thomas, Grant, Andrew D., Hewitt, Ellen, Lindstrom, Erik, Malcangio, Marzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565756/
https://www.ncbi.nlm.nih.gov/pubmed/31223140
http://dx.doi.org/10.1016/j.ynpai.2019.100032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565756/
https://www.ncbi.nlm.nih.gov/pubmed/31223140
http://dx.doi.org/10.1016/j.ynpai.2019.100032

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