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Cathepsin S acts via protease-activated receptor 2 to activate sensory neurons and induce itch-like behaviour
Chronic itch is a debilitating condition characterised by excessive scratching and is a symptom frequently reported in skin diseases such as atopic dermatitis. It has been proposed that release of the cysteine protease Cathepsin S (CatS) from skin keratinocytes or immune cells resident in or infiltr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565756/ https://www.ncbi.nlm.nih.gov/pubmed/31223140 http://dx.doi.org/10.1016/j.ynpai.2019.100032 |