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Impaired mitochondrial respiration in human carotid plaque atherosclerosis: A potential role for Pink1 in vascular smooth muscle cell energetics

BACKGROUND AND AIMS: DNA damage and mitochondrial dysfunction are thought to play an essential role in ageing and the energetic decline of vascular smooth muscle cells (VSMCs) essential for maintaining plaque integrity. We aimed to better understand VSMCs and identify potentially useful compensatory...

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Detalles Bibliográficos
Autores principales: Docherty, Craig K., Carswell, Andy, Friel, Elaine, Mercer, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565844/
https://www.ncbi.nlm.nih.gov/pubmed/29156421
http://dx.doi.org/10.1016/j.atherosclerosis.2017.11.009