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Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling

Neurogenesis in specific brain regions in adult mammals decreases with age. Progressive reduction in the proliferation of neural stem and progenitor cells (NS/PCs) is a primary cause of this age-associated decline. However, the mechanism responsible for this reduction is poorly understood. We identi...

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Detalles Bibliográficos
Autores principales: Kase, Yoshitaka, Otsu, Kinya, Shimazaki, Takuya, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565990/
https://www.ncbi.nlm.nih.gov/pubmed/31080114
http://dx.doi.org/10.1016/j.stemcr.2019.04.010