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Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling
Neurogenesis in specific brain regions in adult mammals decreases with age. Progressive reduction in the proliferation of neural stem and progenitor cells (NS/PCs) is a primary cause of this age-associated decline. However, the mechanism responsible for this reduction is poorly understood. We identi...
Autores principales: | Kase, Yoshitaka, Otsu, Kinya, Shimazaki, Takuya, Okano, Hideyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565990/ https://www.ncbi.nlm.nih.gov/pubmed/31080114 http://dx.doi.org/10.1016/j.stemcr.2019.04.010 |
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