Cargando…

Fluorofenidone affects hepatic stellate cell activation in hepatic fibrosis by targeting the TGF-β1/Smad and MAPK signaling pathways

The aim of the present research was to study the therapeutic impacts of fluorofenidone (AKF-PD) on pig serum (PS)-induced liver fibrosis in rats and the complex molecular mechanisms of its effects on hepatic stellate cells (HSCs). Wistar rats were randomly divided into normal control, PS and PS/AKF-...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Yu, Li, Li, Zhang, Xin, Xie, Mingyan, Yang, Congying, Tu, Sha, Shen, Hong, Hu, Gaoyun, Tao, Lijian, Yang, Huixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566051/
https://www.ncbi.nlm.nih.gov/pubmed/31258636
http://dx.doi.org/10.3892/etm.2019.7548