Probing and regulating the activity of cellular enzymes by using DNA tetrahedron nanostructures

Given the essential role of apurinic/apyrimidinic endonuclease (APE1) in gene repair and cancer progression, we report a novel approach for probing and regulating cellular APE1 activity by using DNA tetrahedrons. The tetrahedron with an AP site-containing antenna exhibits high sensitivity and specif...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Deng, Yingnan, Wang, Congshan, Li, Lidan, Xu, Lida, Yu, Yingjie, Su, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566069/
https://www.ncbi.nlm.nih.gov/pubmed/31360402
http://dx.doi.org/10.1039/c9sc01912j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566069/
https://www.ncbi.nlm.nih.gov/pubmed/31360402
http://dx.doi.org/10.1039/c9sc01912j

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