A Peptide Inhibitor of NADPH Oxidase (NOX2) Activation Markedly Decreases Mouse Lung Injury and Mortality Following Administration of Lipopolysaccharide (LPS)

We have previously derived three related peptides, based on a nine-amino acid sequence in human or rat/mouse surfactant protein A, that inhibit the phospholipase A(2) activity of peroxiredoxin 6 (Prdx6) and prevent the activation of lung NADPH oxidase (type 2). The present study evaluated the effect...

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Detalles Bibliográficos
Autores principales: Fisher, Aron B., Dodia, Chandra, Chatterjee, Shampa, Feinstein, Sheldon I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566262/
https://www.ncbi.nlm.nih.gov/pubmed/31096551
http://dx.doi.org/10.3390/ijms20102395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566262/
https://www.ncbi.nlm.nih.gov/pubmed/31096551
http://dx.doi.org/10.3390/ijms20102395

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