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Molecular Docking and Molecular Dynamics (MD) Simulation of Human Anti-Complement Factor H (CFH) Antibody Ab42 and CFH Polypeptide

An understanding of the interaction between the antibody and its targeted antigen and knowing of the epitopes are critical for the development of monoclonal antibody drugs. Complement factor H (CFH) is implied to play a role in tumor growth and metastasis. An autoantibody to CHF is associated with a...

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Detalles Bibliográficos
Autores principales: Yang, Bing, Lin, Shu-Jian, Ren, Jia-Yi, Liu, Tong, Wang, Yue-Ming, Li, Cheng-Ming, Xu, Wen-Wen, He, You-Wen, Zheng, Wei-Hong, Zhao, Jian, Yuan, Xiao-Hui, Liao, Hua-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566401/
https://www.ncbi.nlm.nih.gov/pubmed/31130605
http://dx.doi.org/10.3390/ijms20102568