Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates

The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates forming acyclic all-carbon quaternary stereocenters is reported. Excellent yields up to 99% and enantioselectivities up to 98% ee are obtained through the use...

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Detalles Bibliográficos
Autores principales: Alexy, Eric J., Fulton, Tyler J., Zhang, Haiming, Stoltz, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566452/
https://www.ncbi.nlm.nih.gov/pubmed/31360407
http://dx.doi.org/10.1039/c9sc01726g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566452/
https://www.ncbi.nlm.nih.gov/pubmed/31360407
http://dx.doi.org/10.1039/c9sc01726g

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