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Robustness of testing procedures for confirmatory subpopulation analyses based on a continuous biomarker
With the advent of personalized medicine, clinical trials studying treatment effects in subpopulations are receiving increasing attention. The objectives of such studies are, besides demonstrating a treatment effect in the overall population, to identify subpopulations, based on biomarkers, where th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566459/ https://www.ncbi.nlm.nih.gov/pubmed/29888651 http://dx.doi.org/10.1177/0962280218777538 |