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Cysteinylprolyl imide (CPI) peptide: a highly reactive and easily accessible crypto-thioester for chemical protein synthesis

Native chemical ligation (NCL) between the C-terminal peptide thioester and the N-terminal cysteinyl-peptide revolutionized the field of chemical protein synthesis. The difficulty of direct synthesis of the peptide thioester in the Fmoc method has prompted the development of crypto-thioesters that c...

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Detalles Bibliográficos
Autores principales: Yanase, Masafumi, Nakatsu, Koki, Cardos, Charlane Joy, Konda, Yoshiki, Hayashi, Gosuke, Okamoto, Akimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566460/
https://www.ncbi.nlm.nih.gov/pubmed/31360403
http://dx.doi.org/10.1039/c9sc00646j