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Small Interference RNA Targeting Connexin-43 Improves Motor Function and Limits Astrogliosis After Juvenile Traumatic Brain Injury

Juvenile traumatic brain injury (jTBI) is the leading cause of death and disability for children and adolescents worldwide, but there are no pharmacological treatments available. Aquaporin 4 (AQP4), an astrocytic perivascular protein, is increased after jTBI, and inhibition of its expression with sm...

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Detalles Bibliográficos
Autores principales: Ichkova, Aleksandra, Fukuda, Andrew M., Nishiyama, Nina, Paris, Germaine, Obenaus, Andre, Badaut, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566476/
https://www.ncbi.nlm.nih.gov/pubmed/31194577
http://dx.doi.org/10.1177/1759091419847090