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The influence of SLC22A1 rs622342 and ABCC8 rs757110 genetic variants on the efficacy of metformin and glimepiride combination therapy in Egyptian patients with type 2 diabetes

Background: The incidence of Type 2 Diabetes Mellitus (T2DM) in Egypt is considered one of the highest in the world. Metformin and Sulfonylureas are usually prescribed together due to their efficacy and their relatively low cost. Organic cation transport 1, encoded by SLC22A1 gene, is the main trans...

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Detalles Bibliográficos
Autores principales: Ebid, Abdel-Hameed I. M., Ehab, Moataz, Ismail, Ashraf, Soror, Sameh, Mahmoud, Mohamed Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566583/
https://www.ncbi.nlm.nih.gov/pubmed/31231590
http://dx.doi.org/10.1080/21556660.2019.1619571