Histone deacetylase 6 interference protects mice against experimental stroke-induced brain injury via activating Nrf2/HO-1 pathway

Cerebral stroke is a fatal disease with increasing incidence. The study was to investigate the role and mechanism of Histone deacetylase 6 (HDAC6) on experimental stroke-induced brain injury. The recombinant shRNA-HDAC6 or scramble shRNA lentivirus was transfected to ICR mice. Then, the ischemia/rep...

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Detalles Bibliográficos
Autores principales: Li, Jie, Zhao, Yanping, Shi, Junfeng, Ren, Zhanyun, Chen, Feng, Tang, Wuzhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Neurobiology & Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566595/
https://www.ncbi.nlm.nih.gov/pubmed/31231583
http://dx.doi.org/10.1080/19768354.2019.1601132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566595/
https://www.ncbi.nlm.nih.gov/pubmed/31231583
http://dx.doi.org/10.1080/19768354.2019.1601132

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