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ERK is a Pivotal Player of Chemo-Immune-Resistance in Cancer

The extracellular signal-related kinases (ERKs) act as pleiotropic molecules in tumors, where they activate pro-survival pathways leading to cell proliferation and migration, as well as modulate apoptosis, differentiation, and senescence. Given its central role as sensor of extracellular signals, ER...

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Detalles Bibliográficos
Autores principales: Salaroglio, Iris C., Mungo, Eleonora, Gazzano, Elena, Kopecka, Joanna, Riganti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566596/
https://www.ncbi.nlm.nih.gov/pubmed/31117237
http://dx.doi.org/10.3390/ijms20102505