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Dysregulation of Neuronal Genes by Fetal-Neonatal Iron Deficiency Anemia Is Associated with Altered DNA Methylation in the Rat Hippocampus

Early-life iron deficiency results in long-term abnormalities in cognitive function and affective behavior in adulthood. In preclinical models, these effects have been associated with long-term dysregulation of key neuronal genes. While limited evidence suggests histone methylation as an epigenetic...

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Detalles Bibliográficos
Autores principales: Lien, Yu-Chin, Condon, David E, Georgieff, Michael K, Simmons, Rebecca A, Tran, Phu V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566599/
https://www.ncbi.nlm.nih.gov/pubmed/31137889
http://dx.doi.org/10.3390/nu11051191