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Zoledronate induces cell cycle arrest and differentiation by upregulating p21 in mouse MC3T3-E1 preosteoblasts

Background: Increasing research has recently been focused on the supplementary use of drugs such as bisphosphonates that are known to influence bone turnover to prevent and treat periprosthetic bone loss and subsequent implant loosening following total joint replacements. However, there are still co...

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Detalles Bibliográficos
Autores principales: Huang, Kuo-Chin, Huang, Tsan-Wen, Chuang, Po-Yao, Yang, Tien-Yu, Chang, Shun-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566742/
https://www.ncbi.nlm.nih.gov/pubmed/31217743
http://dx.doi.org/10.7150/ijms.32612