Direct Enantiomeric Resolution of Seventeen Racemic 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives by HPLC

1,4-Dihydropyridine (DHP) scaffold holds an outstanding position with its versatile pharmacological properties among all heterocyclic compounds. Although most of the commercially available DHPs are marketed as a racemic mixture, the chiral center at C-4 can lead to even opposite pharmacological acti...

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Detalles Bibliográficos
Autores principales: Sun, Jiayi, Gözde Gündüz, Miyase, Zhang, Junyuan, Yu, Jia, Guo, Xingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566779/
https://www.ncbi.nlm.nih.gov/pubmed/31121823
http://dx.doi.org/10.3390/ijms20102513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566779/
https://www.ncbi.nlm.nih.gov/pubmed/31121823
http://dx.doi.org/10.3390/ijms20102513

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