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Cyclodextrin–Amphiphilic Copolymer Supramolecular Assemblies for the Ocular Delivery of Natamycin

Natamycin is the only drug approved for fungal keratitis treatment, but its low water solubility and low ocular penetration limit its efficacy. The purpose of this study was to overcome these limitations by encapsulating the drug in single or mixed micelles and poly(pseudo)rotaxanes. Soluplus and Pl...

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Detalles Bibliográficos
Autores principales: Lorenzo-Veiga, Blanca, Sigurdsson, Hakon Hrafn, Loftsson, Thorsteinn, Alvarez-Lorenzo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566826/
https://www.ncbi.nlm.nih.gov/pubmed/31096569
http://dx.doi.org/10.3390/nano9050745