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Cyclodextrin–Amphiphilic Copolymer Supramolecular Assemblies for the Ocular Delivery of Natamycin
Natamycin is the only drug approved for fungal keratitis treatment, but its low water solubility and low ocular penetration limit its efficacy. The purpose of this study was to overcome these limitations by encapsulating the drug in single or mixed micelles and poly(pseudo)rotaxanes. Soluplus and Pl...
Autores principales: | Lorenzo-Veiga, Blanca, Sigurdsson, Hakon Hrafn, Loftsson, Thorsteinn, Alvarez-Lorenzo, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566826/ https://www.ncbi.nlm.nih.gov/pubmed/31096569 http://dx.doi.org/10.3390/nano9050745 |
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