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The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Ameliorates High-fat Induced Cognitive Decline in Tauopathy Model Mice

Vascular risk factors, such as type 2 diabetes mellitus (T2DM), are associated with the increased risk of Alzheimer’s disease. One of the common T2DM medications, dipeptidyl peptidase (DPP)-4 inhibitors, have a minimum risk for hypoglycemia and have recently been suggested to ameliorate β-amyloid pa...

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Detalles Bibliográficos
Autores principales: Nakaoku, Yuriko, Saito, Satoshi, Yamamoto, Yumi, Maki, Takakuni, Takahashi, Ryosuke, Ihara, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566831/
https://www.ncbi.nlm.nih.gov/pubmed/31126115
http://dx.doi.org/10.3390/ijms20102539