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Endothelin-converting enzyme-1 expression in acute and chronic liver injury in fibrogenesis

Endothelin-1 (ET-1) induces contraction, proliferation, and collagen synthesis of activated hepatic stellate cells and is a potent mediator of portal hypertension. Endothelin-converting enzyme-1 (ECE-1) generates ET-1 from the inactive precursor big-endothelin-1. The cellular distribution and activi...

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Detalles Bibliográficos
Autores principales: Cho, Tae-Jun, Kim, Hyo-Jung, Cho, Jaejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566842/
https://www.ncbi.nlm.nih.gov/pubmed/31231580
http://dx.doi.org/10.1080/19768354.2019.1595141