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Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death

High levels of heme oxygenase (HO)-1 have been frequently reported in different human cancers, playing a major role in drug resistance and regulation of cancer cell redox homeostasis. Metformin (MET), a drug widely used for type 2 diabetes, has recently gained interest for treating several cancers....

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Detalles Bibliográficos
Autores principales: Raffaele, Marco, Pittalà, Valeria, Zingales, Veronica, Barbagallo, Ignazio, Salerno, Loredana, Li Volti, Giovanni, Romeo, Giuseppe, Carota, Giuseppe, Sorrenti, Valeria, Vanella, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566853/
https://www.ncbi.nlm.nih.gov/pubmed/31137785
http://dx.doi.org/10.3390/ijms20102593