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Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death
High levels of heme oxygenase (HO)-1 have been frequently reported in different human cancers, playing a major role in drug resistance and regulation of cancer cell redox homeostasis. Metformin (MET), a drug widely used for type 2 diabetes, has recently gained interest for treating several cancers....
Autores principales: | Raffaele, Marco, Pittalà, Valeria, Zingales, Veronica, Barbagallo, Ignazio, Salerno, Loredana, Li Volti, Giovanni, Romeo, Giuseppe, Carota, Giuseppe, Sorrenti, Valeria, Vanella, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566853/ https://www.ncbi.nlm.nih.gov/pubmed/31137785 http://dx.doi.org/10.3390/ijms20102593 |
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