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Zebrafish model of KRAS-initiated pancreatic endocrine tumor

Pancreatic cancer constitutes a genetic disease in which somatic mutations in the KRAS proto-oncogene are detected in 95% of cases. Activation of the KRAS proto-oncogene represents an initiating event in pancreatic tumorigenesis. Here, we established a zebrafish pancreatic neoplasia model that recap...

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Detalles Bibliográficos
Autores principales: Oh, Sekyung, Park, Joon Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566937/
https://www.ncbi.nlm.nih.gov/pubmed/31231585
http://dx.doi.org/10.1080/19768354.2019.1610058